Transcript 1. Summary of molecular genetics paradigm

1. Summary of molecular genetics paradigm
2. Griffith – ‘transforming principle’
3. Hershey & Chase confirm DNA is genetic material
4. Watson & Crick – double helix model
5. Franklin – X-ray crystallographer
6. Purine-pyrimidine pairs fit X-ray data
7. Complementary base pairs in DNA
8. Double stranded DNA has antiparallel strands
9. Definitive features of double helix model
10. Basic template copy concept
11. Prospective models for replication
12. Meselson & Stahl confirmed semiconservative model
13. Replication origins, bubbles & forks
14. Template copy mechanism
15. Continuous & discontinuous replication
16. RNA primer & primase enzyme
17. Summary of steps in DNA replication
18. Enzymes of DNA replication
19. DNA repair