Transcript Adjust your seat… Hafdzi Maulana Aang Setiawan Todia Pediatama ANTI-HYPERTENSIVE AGENT OF CORN SILK EXTRACT AS PREVENTIVE METHOD IN VASCULAR HYPERTENSIVE DISEASE.

Adjust your seat…
Hafdzi Maulana
Aang Setiawan
Todia Pediatama
ANTI-HYPERTENSIVE AGENT OF CORN SILK EXTRACT
AS PREVENTIVE METHOD
IN VASCULAR HYPERTENSIVE DISEASE
1.
2.
3.
4.
The Impact of Chronic Disease in Indonesia. Available from : http://www/who/int/chp/chronic_disease_report/en/.
Kumar, R., Abbas, A., DeLancey, A., and Malone, E. Robbin and Cotran Pathologic Basis of Disease. ed 8. US. 2010: 529585.
Kasper, Braunwald, Fauci, Hauser, Longo and Jameson. Harrison’s Principles of Internal Medicine. ed 16. US. 2005:
1463-1480.
Mycek, M.J., Harvey, R.A., and Champe, P.C. Lippincott’s Illustrated Reviews: Pharmacology. ed 2. US. p 157.
Objective
To describe and give basic understanding of
corn silk as preventive method in VHD.
Benefit
For future research on providing deeper
knowledge for effectiveness of corn silk.
Data Synthesis
&
Discussion
Data Synthesis
Keywords :
Corn Silk
• Contain
Jurnal
Jurnal
Hypertension
• Etiology
Jurnal
Searching
engine
Corn Silk
Hypertension
TASSEL
LEAF
???
EAR
Zea mays or known as corn. From genus Zea L.. Species Zea mays L.(1)
Corn Silk (maydis
Stigma)
STALK
COB (kernels)
Treatment of
Cystits, gout,
nephritis,
benign prostatic
hyperplasia (2)
1. Taxonomy and Nomenclature of Zea Mays L. 2012; Available from:
ttp://www.itis.gov/servlet/SingleRpt/SingleRpt?search_topic=TSN&search_value=42269
2. Maksimovic, Z., Malencic, D. and Kovacevic, N. (2005) Polyphenol contents and antioxidant activity of Maydis stigma extracts. Bioresource
Technology 96, 873-877.
Corn Silk
Hypertension
Hypertension which is unknown cause called
primary hypertension (also called essential and
idiopathic hypertension), and hypertension which
is known cause called secondary hypertension.
[25]http://medical-dictionary.thefreedictionary.com/hypertension
(10/3/2012)
Classification of Hypertension
No.
Blood Pressure
Classification
Systolic
Diastolic
1.
Normal
<120
<80
2.
Prehypertension (PH)
120-139
or 80-89
3.
Stage 1 hypertension
140-159
or 90-99
4.
Stage 2 hypertension
≥160
≥100
5.
Isolated systolic
hypertension
≥140
<90
[26]
[26]Fauci,
Anthony., Kasper, Denis., Harrison’s Internal Medicine.Ed.18.USA:McGraw-Hill’s.2009
Criteria of People in High
Risk of Hypertension
Improper diet
Obesity
Lain-lain
[29,30]
•
Moser, Marvin. Heart Book. USA : Yale University.
Shijiazhuang Kidney Disease Hospital. http://kidneycn.com (16/03/2012)
Smoking
Treatments
Back
Non-pharmacologic[31]
Green Tea[32]
[31]
Pharmacologic
Non-pharmaco
&
Pharmacologic
[31]
[31]
Corn Silk[15]
Crawford, Michael. CURRENT Diagnosis & Treatment in CARDIOLOGY. Ed.2. USA: Mac Graw Hill.
Michele., Montemuro, Domenico., Bolognesi, Massimo., Pasoli, Di Marco., Piva, Anna., Grego, Franco., Sticchi,
Danielle., Giuliani, Luisa., Garbisa, Spiridro. and Rossi, Gian Paolo. 2007. Prevention of Hypertension, Cardiovascular
Damage & Endothelial Dysfunction with Green Tea Extracts.Italy.
[15]Hu Q-L, Deng Z-H. Protective effects of flavonoid from corn silk on oxidative stress induced by exhaustive exercise in mice.
African Journal of Biotechnology. 2011;10(16):3163-7.
[32]Antonello,
High Risk
High blood
glucose
High LDL
• Obese
• Improper Diet
• Diabetes
• Smoking, etc.
Flavonoid
Fe+ chelating
Tannic Acid
Flavonoid &
Sapponin
adipogenesis
Minerals
Water & Na retention
Atherosclerosis
High
cholesterol
Hypertension
Discussion
It has several compound and activity as anti-oxidant
agent, anti-inflammation, and anti-hyperlipidemia, that plays as
hypertensive agent. Comparing to current preventive method e.g.
green tea that works as anti-oxidant, corn silk is more effective to
work. It is low-cost, and easy-found.
Further research is considerably recommended in
Indonesia. Also, the research in effectiveness of corn silk should
be held in future.
Conclusion